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In vitro RNA interference targeting the DNA polymerase gene inhibits orf virus replication in primary ovine fetal turbinate cells

Orf, which is caused by orf virus (ORFV), is distributed worldwide and is endemic in most sheep- and/or goat-raising countries. RNA interference (RNAi) pathways have emerged as important regulators of virus-host cell interactions. In this study, the specific effect of RNAi on the replication of ORFV...

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Detalles Bibliográficos
Autores principales: Wang, Gaili, He, Wenqi, Song, Deguang, Li, Jida, Bao, Yingfu, Lu, Rongguang, Bi, Jingying, Zhao, Kui, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010719/
https://www.ncbi.nlm.nih.gov/pubmed/24178308
http://dx.doi.org/10.1007/s00705-013-1896-z