Targeting TGF-β Signaling by Antisense Oligonucleotide-mediated Knockdown of TGF-β Type I Receptor

Duchenne muscular dystrophy (DMD) is caused by lack of functional dystrophin and results in progressive myofiber damage and degeneration. In addition, impaired muscle regeneration and fibrosis contribute to the progressive pathology of DMD. Importantly, transforming growth factor-β (TGF-β) is implic...

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Detalles Bibliográficos
Autores principales: Kemaladewi, Dwi U, Pasteuning, Svitlana, van der Meulen, Joke W, van Heiningen, Sandra H, van Ommen, Gert-Jan, ten Dijke, Peter, Aartsma-Rus, Annemieke, ‘t Hoen, Peter AC, Hoogaars, Willem M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011125/
https://www.ncbi.nlm.nih.gov/pubmed/24691207
http://dx.doi.org/10.1038/mtna.2014.7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011125/
https://www.ncbi.nlm.nih.gov/pubmed/24691207
http://dx.doi.org/10.1038/mtna.2014.7

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