Methyl 1-ethyl-3′-[hy­droxy(naphthalen-1-yl)meth­yl]-1′-methyl-2-oxo­spiro­[indo­line-3,2′-pyrrolidine]-3′-carboxyl­ate

In the title compound, C(27)H(28)N(2)O(4), the pyrrolidine ring adopts a twist conformation. The plane of the indole ring is almost perpendicular to that of the pyrrolidine ring, making a dihedral angle of 88.50 (6)°. The planes of the naphthyl ring system and the pyrrolidine ring are tilted by an a...

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Autores principales: Vijayakumar, Vinodhkumar, Peters, Gunther H., Suresh, M., Raghavachary, Raghunathan, Jagadeesan, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011217/
https://www.ncbi.nlm.nih.gov/pubmed/24860349
http://dx.doi.org/10.1107/S1600536814007065
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author Vijayakumar, Vinodhkumar
Peters, Gunther H.
Suresh, M.
Raghavachary, Raghunathan
Jagadeesan, G.
author_facet Vijayakumar, Vinodhkumar
Peters, Gunther H.
Suresh, M.
Raghavachary, Raghunathan
Jagadeesan, G.
author_sort Vijayakumar, Vinodhkumar
collection PubMed
description In the title compound, C(27)H(28)N(2)O(4), the pyrrolidine ring adopts a twist conformation. The plane of the indole ring is almost perpendicular to that of the pyrrolidine ring, making a dihedral angle of 88.50 (6)°. The planes of the naphthyl ring system and the pyrrolidine ring are tilted by an angle of 55.86 (5)°. The mol­ecular conformation is stabilized by intra­molecular O—H⋯O and O—H⋯N hydrogen bonds.
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spelling pubmed-40112172014-05-23 Methyl 1-ethyl-3′-[hy­droxy(naphthalen-1-yl)meth­yl]-1′-methyl-2-oxo­spiro­[indo­line-3,2′-pyrrolidine]-3′-carboxyl­ate Vijayakumar, Vinodhkumar Peters, Gunther H. Suresh, M. Raghavachary, Raghunathan Jagadeesan, G. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(27)H(28)N(2)O(4), the pyrrolidine ring adopts a twist conformation. The plane of the indole ring is almost perpendicular to that of the pyrrolidine ring, making a dihedral angle of 88.50 (6)°. The planes of the naphthyl ring system and the pyrrolidine ring are tilted by an angle of 55.86 (5)°. The mol­ecular conformation is stabilized by intra­molecular O—H⋯O and O—H⋯N hydrogen bonds. International Union of Crystallography 2014-04-12 /pmc/articles/PMC4011217/ /pubmed/24860349 http://dx.doi.org/10.1107/S1600536814007065 Text en © Vijayakumar et al. 2014 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Vijayakumar, Vinodhkumar
Peters, Gunther H.
Suresh, M.
Raghavachary, Raghunathan
Jagadeesan, G.
Methyl 1-ethyl-3′-[hy­droxy(naphthalen-1-yl)meth­yl]-1′-methyl-2-oxo­spiro­[indo­line-3,2′-pyrrolidine]-3′-carboxyl­ate
title Methyl 1-ethyl-3′-[hy­droxy(naphthalen-1-yl)meth­yl]-1′-methyl-2-oxo­spiro­[indo­line-3,2′-pyrrolidine]-3′-carboxyl­ate
title_full Methyl 1-ethyl-3′-[hy­droxy(naphthalen-1-yl)meth­yl]-1′-methyl-2-oxo­spiro­[indo­line-3,2′-pyrrolidine]-3′-carboxyl­ate
title_fullStr Methyl 1-ethyl-3′-[hy­droxy(naphthalen-1-yl)meth­yl]-1′-methyl-2-oxo­spiro­[indo­line-3,2′-pyrrolidine]-3′-carboxyl­ate
title_full_unstemmed Methyl 1-ethyl-3′-[hy­droxy(naphthalen-1-yl)meth­yl]-1′-methyl-2-oxo­spiro­[indo­line-3,2′-pyrrolidine]-3′-carboxyl­ate
title_short Methyl 1-ethyl-3′-[hy­droxy(naphthalen-1-yl)meth­yl]-1′-methyl-2-oxo­spiro­[indo­line-3,2′-pyrrolidine]-3′-carboxyl­ate
title_sort methyl 1-ethyl-3′-[hy­droxy(naphthalen-1-yl)meth­yl]-1′-methyl-2-oxo­spiro­[indo­line-3,2′-pyrrolidine]-3′-carboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011217/
https://www.ncbi.nlm.nih.gov/pubmed/24860349
http://dx.doi.org/10.1107/S1600536814007065
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