1′-Allyl-1-(3,4-di­methyl­benzo­yl)-2-(4-methyl-1,3-thia­zol-5-yl)-1,2,5,6,7,7a-hexa­hydro­spiro­[pyrrolizine-3,3′-indolin]-2′-one

In the title compound, C(30)H(31)N(3)O(2)S, the fused pyrrolidine ring bearing three substituents adopts an envelope conformation with the C atom bearing the benzoyl group as the flap. The other fused pyrrolidine ring adopts a twisted conformation about one of its C—C bonds. The dihedral angle betwe...

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Detalles Bibliográficos
Autores principales: Karthikeyan, V., Ramkumar, V., Karunakaran, R. Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011234/
https://www.ncbi.nlm.nih.gov/pubmed/24860350
http://dx.doi.org/10.1107/S1600536814006990
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author Karthikeyan, V.
Ramkumar, V.
Karunakaran, R. Joel
author_facet Karthikeyan, V.
Ramkumar, V.
Karunakaran, R. Joel
author_sort Karthikeyan, V.
collection PubMed
description In the title compound, C(30)H(31)N(3)O(2)S, the fused pyrrolidine ring bearing three substituents adopts an envelope conformation with the C atom bearing the benzoyl group as the flap. The other fused pyrrolidine ring adopts a twisted conformation about one of its C—C bonds. The dihedral angle between the isatin ring system and the methyl­thia­zole ring is 25.95 (8)°. An intra­molecular C—H⋯O inter­action closes an S(8) ring. In the crystal, mol­ecules are linked by C—H⋯O inter­actions, generating C(11) chains propagating in [001].
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spelling pubmed-40112342014-05-23 1′-Allyl-1-(3,4-di­methyl­benzo­yl)-2-(4-methyl-1,3-thia­zol-5-yl)-1,2,5,6,7,7a-hexa­hydro­spiro­[pyrrolizine-3,3′-indolin]-2′-one Karthikeyan, V. Ramkumar, V. Karunakaran, R. Joel Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(30)H(31)N(3)O(2)S, the fused pyrrolidine ring bearing three substituents adopts an envelope conformation with the C atom bearing the benzoyl group as the flap. The other fused pyrrolidine ring adopts a twisted conformation about one of its C—C bonds. The dihedral angle between the isatin ring system and the methyl­thia­zole ring is 25.95 (8)°. An intra­molecular C—H⋯O inter­action closes an S(8) ring. In the crystal, mol­ecules are linked by C—H⋯O inter­actions, generating C(11) chains propagating in [001]. International Union of Crystallography 2014-04-12 /pmc/articles/PMC4011234/ /pubmed/24860350 http://dx.doi.org/10.1107/S1600536814006990 Text en © Karthikeyan et al. 2014 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Karthikeyan, V.
Ramkumar, V.
Karunakaran, R. Joel
1′-Allyl-1-(3,4-di­methyl­benzo­yl)-2-(4-methyl-1,3-thia­zol-5-yl)-1,2,5,6,7,7a-hexa­hydro­spiro­[pyrrolizine-3,3′-indolin]-2′-one
title 1′-Allyl-1-(3,4-di­methyl­benzo­yl)-2-(4-methyl-1,3-thia­zol-5-yl)-1,2,5,6,7,7a-hexa­hydro­spiro­[pyrrolizine-3,3′-indolin]-2′-one
title_full 1′-Allyl-1-(3,4-di­methyl­benzo­yl)-2-(4-methyl-1,3-thia­zol-5-yl)-1,2,5,6,7,7a-hexa­hydro­spiro­[pyrrolizine-3,3′-indolin]-2′-one
title_fullStr 1′-Allyl-1-(3,4-di­methyl­benzo­yl)-2-(4-methyl-1,3-thia­zol-5-yl)-1,2,5,6,7,7a-hexa­hydro­spiro­[pyrrolizine-3,3′-indolin]-2′-one
title_full_unstemmed 1′-Allyl-1-(3,4-di­methyl­benzo­yl)-2-(4-methyl-1,3-thia­zol-5-yl)-1,2,5,6,7,7a-hexa­hydro­spiro­[pyrrolizine-3,3′-indolin]-2′-one
title_short 1′-Allyl-1-(3,4-di­methyl­benzo­yl)-2-(4-methyl-1,3-thia­zol-5-yl)-1,2,5,6,7,7a-hexa­hydro­spiro­[pyrrolizine-3,3′-indolin]-2′-one
title_sort 1′-allyl-1-(3,4-di­methyl­benzo­yl)-2-(4-methyl-1,3-thia­zol-5-yl)-1,2,5,6,7,7a-hexa­hydro­spiro­[pyrrolizine-3,3′-indolin]-2′-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011234/
https://www.ncbi.nlm.nih.gov/pubmed/24860350
http://dx.doi.org/10.1107/S1600536814006990
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AT karunakaranrjoel 1allyl134dimethylbenzoyl24methyl13thiazol5yl125677ahexahydrospiropyrrolizine33indolin2one

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