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MicroRNA-302b augments host defense to bacteria by regulating inflammatory responses via feedback to TLR/IRAK4 circuits

MicroRNAs (miRNAs) have been implicated in a spectrum of physiological and pathological conditions, including immune responses. miR-302b has been implicated in stem cell differentiation but its role in immunity remains unknown. Here we show that miR-302b is induced by TLR2 and TLR4 through ERK-p38-N...

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Detalles Bibliográficos
Autores principales: Zhou, Xikun, Li, Xuefeng, Ye, Yan, Zhao, Kelei, Zhuang, Yan, Li, Yi, Wei, Yuquan, Wu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011559/
https://www.ncbi.nlm.nih.gov/pubmed/24717937
http://dx.doi.org/10.1038/ncomms4619