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Palladium-Catalyzed Direct Arylation of 5-Halouracils and 5-Halouracil Nucleosides with Arenes and Heteroarenes Promoted by TBAF
[Image: see text] The 1-N-benzyl-5-iodo(or bromo)uracil undergoes Pd-catalyzed [Pd(2)(dba)(3)] direct arylation with benzene and other simple arenes in the presence of TBAF in DMF without the necessity of adding any ligands or additives to give 5-arylated uracil analogues. The TBAF-promoted coupling...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011569/ https://www.ncbi.nlm.nih.gov/pubmed/24724921 http://dx.doi.org/10.1021/jo500602p |