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Palladium-Catalyzed Direct Arylation of 5-Halouracils and 5-Halouracil Nucleosides with Arenes and Heteroarenes Promoted by TBAF

[Image: see text] The 1-N-benzyl-5-iodo(or bromo)uracil undergoes Pd-catalyzed [Pd(2)(dba)(3)] direct arylation with benzene and other simple arenes in the presence of TBAF in DMF without the necessity of adding any ligands or additives to give 5-arylated uracil analogues. The TBAF-promoted coupling...

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Detalles Bibliográficos
Autores principales:	Liang, Yong, Gloudeman, Jennifer, Wnuk, Stanislaw F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011569/ https://www.ncbi.nlm.nih.gov/pubmed/24724921 http://dx.doi.org/10.1021/jo500602p

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