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Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene
Cancers arise through accumulating genetic and epigenetic alterations, considered relevant for phenotype and approaches to targeting new therapies. We investigated a unique collection of endometrial cancer precursor samples and clinically annotated primary and metastatic lesions for two evolutionary...
Autores principales: | Hoivik, Erling A., Kusonmano, Kanthida, Halle, Mari K., Berg, Anna, Wik, Elisabeth, Werner, Henrica M. J., Petersen, Kjell, Oyan, Anne M., Kalland, Karl-Henning, Krakstad, Camilla, Trovik, Jone, Widschwendter, Martin, Salvesen, Helga B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011582/ https://www.ncbi.nlm.nih.gov/pubmed/24658009 |
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