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Functional analysis of MKP-1 and MKP-2 in breast cancer tamoxifen sensitivity

Increased activation of ERK signaling has been reported in breast cancer models of acquired tamoxifen resistance. Here, we examined the expression of Mitogen-Activated Protein Kinase Phosphatases (MKPs) 1 and 2 following tamoxifen treatment and the effects of MKP-1/MKP-2 overexpression on tamoxifen...

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Detalles Bibliográficos
Autores principales:	Haagenson, Kelly K., Zhang, Jessica Wei, Xu, Zhengfan, Shekhar, Malathy P.V., Wu, Gen Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011587/ https://www.ncbi.nlm.nih.gov/pubmed/24658355

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