Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma

Glioblastoma remains one of the deadliest of human cancers, with most patients succumbing to the disease within two years of diagnosis. The available data suggest that simultaneous inactivation of critical nodes within the glioblastoma molecular circuitry will be required for meaningful clinical eff...

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Detalles Bibliográficos
Autores principales: Li, Jie, Zhu, Shan, Kozono, David, Ng, Kimberly, Futalan, Diahnn, Shen, Ying, Akers, Johnny C., Steed, Tyler, Kushwaha, Deepa, Schlabach, Michael, Carter, Bob S., Kwon, Chang-Hyuk, Furnari, Frank, Cavenee, Webster, Elledge, Stephen, Chen, Clark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011590/
https://www.ncbi.nlm.nih.gov/pubmed/24658464

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