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LZTS1 downregulation confers paclitaxel resistance and is associated with worse prognosis in breast cancer

The Leucine Zipper Tumor Suppressor 1 (LZTS1) is a tumor suppressor gene, located at chromosome 8p22, which is frequently altered in human cancer. In normal tissue, its ubiquitous expression regulates cell mitosis by the stabilization of microtubule networks. LZTS1-deficient mouse embryonic fibrobla...

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Detalles Bibliográficos
Autores principales:	Lovat, Francesca, Ishii, Hideshi, Schiappacassi, Monica, Fassan, Matteo, Barbareschi, Mattia, Galligioni, Enzo, Gasparini, Pierluigi, Baldassarre, Gustavo, Croce, Carlo M., Vecchione, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2013
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011598/ https://www.ncbi.nlm.nih.gov/pubmed/24448468

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