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Reduced Gamma Oscillations in a Mouse Model of Intellectual Disability: A Role for Impaired Repetitive Neurotransmission?
Intellectual disability affects 2–3% of the population; mutations of the X-chromosome are a major cause of moderate to severe cases. The link between the molecular consequences of the mutation and impaired cognitive function remains unclear. Loss of function mutations of oligophrenin-1 (OPHN1) disru...
Autores principales: | Powell, Andrew D., Saintot, Pierre-Philippe, Gill, Kalbinder K., Bharathan, Ashtami, Buck, S. Caroline, Morris, Gareth, Jiruska, Premysl, Jefferys, John G. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011727/ https://www.ncbi.nlm.nih.gov/pubmed/24800744 http://dx.doi.org/10.1371/journal.pone.0095871 |
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