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Glucocorticoid Receptor Knockdown Decreases the Antioxidant Protection of B16 Melanoma Cells: An Endocrine System-Related Mechanism that Compromises Metastatic Cell Resistance to Vascular Endothelium-Induced Tumor Cytotoxicity
We previously reported an interorgan system in which stress-related hormones (corticosterone and noradrenaline), interleukin-6, and glutathione (GSH) coordinately regulate metastatic growth of highly aggressive B16-F10 melanoma cells. Corticosterone, at levels measured in tumor-bearing mice, also in...
Autores principales: | Obrador, Elena, Valles, Soraya L., Benlloch, María, Sirerol, J. Antoni, Pellicer, José A., Alcácer, Javier, Coronado, Javier Alcácer-F., Estrela, José M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011753/ https://www.ncbi.nlm.nih.gov/pubmed/24802641 http://dx.doi.org/10.1371/journal.pone.0096466 |
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