Thorax irradiation triggers a local and systemic accumulation of immunosuppressive CD4+ FoxP3+ regulatory T cells

BACKGROUND: Lymphocyte infiltration is a common feature of radiation-induced pneumonitis and fibrosis, but their contribution to the pathogenic processes is still unclear. Here, we addressed the impact of thorax irradiation on the T cell compartment with a focus on immunosuppressive regulatory T cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Wirsdörfer, Florian, Cappuccini, Federica, Niazman, Muska, de Leve, Simone, Westendorf, Astrid M, Lüdemann, Lutz, Stuschke, Martin, Jendrossek, Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011772/
https://www.ncbi.nlm.nih.gov/pubmed/24766907
http://dx.doi.org/10.1186/1748-717X-9-98

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011772/
https://www.ncbi.nlm.nih.gov/pubmed/24766907
http://dx.doi.org/10.1186/1748-717X-9-98

Ejemplares similares