Polyclonal activation of naïve T cells by urease deficient-recombinant BCG that produced protein complex composed of heat shock protein 70, CysO and major membrane protein-II

BACKGROUND: Mycobacterium bovis bacillus Calmette-Guérin (BCG) is known to be only partially effective in inhibiting M. tuberculosis (MTB) multiplication in human. A new recombinant (r) urease-deficient BCG (BCG-dHCM) that secretes protein composed of heat shock protein (HSP)70, MTB-derived CysO and...

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Detalles Bibliográficos
Autores principales: Tsukamoto, Yumiko, Maeda, Yumi, Tamura, Toshiki, Mukai, Tetsu, Makino, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011778/
https://www.ncbi.nlm.nih.gov/pubmed/24690183
http://dx.doi.org/10.1186/1471-2334-14-179

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