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Growth Factor Independence 1b (Gfi1b) Is Important for the Maturation of Erythroid Cells and the Regulation of Embryonic Globin Expression
Growth factor independence 1b (GFI1B) is a DNA binding repressor of transcription with vital functions in hematopoiesis. Gfi1b-null embryos die at midgestation very likely due to defects in erythro- and megakaryopoiesis. To analyze the full functionality of Gfi1b, we used conditionally deficient mic...
Autores principales: | Vassen, Lothar, Beauchemin, Hugues, Lemsaddek, Wafaa, Krongold, Joseph, Trudel, Marie, Möröy, Tarik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011847/ https://www.ncbi.nlm.nih.gov/pubmed/24800817 http://dx.doi.org/10.1371/journal.pone.0096636 |
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