Advantages of Repeated Low Dose against Single High Dose of Kainate in C57BL/6J Mouse Model of Status Epilepticus: Behavioral and Electroencephalographic Studies

A refined kainate (KA) C57BL/6J mouse model of status epilepticus (SE) using a repeated low dose (RLD) of KA (5 mg/kg, intraperitoneal; at 30 min intervals) was compared with the established single high dose (SHD) of KA (20 mg/kg, intraperitoneal) model. In the RLD group, increased duration of convu...

Descripción completa

Detalles Bibliográficos
Autores principales: Tse, Karen, Puttachary, Sreekanth, Beamer, Edward, Sills, Graeme J., Thippeswamy, Thimmasettappa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011859/
https://www.ncbi.nlm.nih.gov/pubmed/24802808
http://dx.doi.org/10.1371/journal.pone.0096622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011859/
https://www.ncbi.nlm.nih.gov/pubmed/24802808
http://dx.doi.org/10.1371/journal.pone.0096622

Ejemplares similares