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Upregulation of Gelatinases and Epithelial–Mesenchymal Transition in Small Airway Remodeling Associated with Chronic Exposure to Wood Smoke

BACKGROUND: Peribronchiolar fibrosis is an important feature of small airway remodeling (SAR) in cigarette smoke-induced COPD. The aim of this study was to investigate the role of gelatinases (MMP9, MMP2) and epithelial-mesenchymal transition (EMT) in SAR related to wood smoke (WS) exposure in a rat...

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Detalles Bibliográficos
Autores principales:	Zou, Yimin, Li, Shaoxing, Zou, Weifeng, Hu, Guoping, Zhou, Yumin, Peng, Gongyong, He, Fang, Li, Bing, Ran, Pixin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011965/ https://www.ncbi.nlm.nih.gov/pubmed/24802298 http://dx.doi.org/10.1371/journal.pone.0096708

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