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TLR dependent XBP-1 activation induces an autocrine loop in rheumatoid arthritis synoviocytes()

X-box binding protein 1 (XBP1) is a central regulator of the endoplasmic reticulum (ER) stress response. It is induced via activation of the IRE1 stress sensor as part of the unfolded protein response (UPR) and has been implicated in several diseases processes. XBP1 can also be activated in direct r...

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Detalles Bibliográficos
Autores principales:	Savic, Sinisa, Ouboussad, Lylia, Dickie, Laura J., Geiler, Janina, Wong, Chi, Doody, Gina M., Churchman, Sarah M., Ponchel, Frederique, Emery, Paul, Cook, Graham P., Buch, Maya H., Tooze, Reuben M., McDermott, Michael F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012140/ https://www.ncbi.nlm.nih.gov/pubmed/24387801 http://dx.doi.org/10.1016/j.jaut.2013.11.002

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