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Analysis pipeline for the epistasis search – statistical versus biological filtering

Gene–gene interactions may contribute to the genetic variation underlying complex traits but have not always been taken fully into account. Statistical analyses that consider gene–gene interaction may increase the power of detecting associations, especially for low-marginal-effect markers, and may e...

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Detalles Bibliográficos
Autores principales: Sun, Xiangqing, Lu, Qing, Mukherjee, Shubhabrata, Crane, Paul K., Elston, Robert, Ritchie, Marylyn D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012196/
https://www.ncbi.nlm.nih.gov/pubmed/24817878
http://dx.doi.org/10.3389/fgene.2014.00106