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CARF and WYL domains: ligand-binding regulators of prokaryotic defense systems

CRISPR-Cas adaptive immunity systems of bacteria and archaea insert fragments of virus or plasmid DNA as spacer sequences into CRISPR repeat loci. Processed transcripts encompassing these spacers guide the cleavage of the cognate foreign DNA or RNA. Most CRISPR-Cas loci, in addition to recognized ca...

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Detalles Bibliográficos
Autores principales:	Makarova, Kira S., Anantharaman, Vivek, Grishin, Nick V., Koonin, Eugene V., Aravind, L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012209/ https://www.ncbi.nlm.nih.gov/pubmed/24817877 http://dx.doi.org/10.3389/fgene.2014.00102

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