Receptor Pre-Clustering and T cell Responses: Insights into Molecular Mechanisms

T cell activation, initiated by T cell receptor (TCR) mediated recognition of pathogen-derived peptides presented by major histocompatibility complex class I or II molecules (pMHC), shows exquisite specificity and sensitivity, even though the TCR–pMHC binding interaction is of low affinity. Recent e...

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Detalles Bibliográficos
Autores principales: Castro, Mario, van Santen, Hisse M., Férez, María, Alarcón, Balbino, Lythe, Grant, Molina-París, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012210/
https://www.ncbi.nlm.nih.gov/pubmed/24817867
http://dx.doi.org/10.3389/fimmu.2014.00132

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