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Parental inconsistency, impulsive choice and neural value representations in healthy adolescents

A well-characterized potential marker for addiction is impulsive choice, stably measured by delay discounting (DD) paradigms. While genetic influences partly account for inter-individual variance in impulsivity, environmental factors such as parenting practices may have an important role. The presen...

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Autores principales: Schneider, S, Peters, J, Peth, J M, Büchel, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012284/
https://www.ncbi.nlm.nih.gov/pubmed/24736798
http://dx.doi.org/10.1038/tp.2014.20
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author Schneider, S
Peters, J
Peth, J M
Büchel, C
author_facet Schneider, S
Peters, J
Peth, J M
Büchel, C
author_sort Schneider, S
collection PubMed
description A well-characterized potential marker for addiction is impulsive choice, stably measured by delay discounting (DD) paradigms. While genetic influences partly account for inter-individual variance in impulsivity, environmental factors such as parenting practices may have an important role. The present study investigates how inconsistent fulfillment of delayed reward promises impacts on DD. A combined correlational and experimental functional magnetic resonance imaging (fMRI) design was performed in a sample of 48 healthy adolescents (13–15 years). More specifically, neural activation during a DD task was investigated at two assessment points (T(0) and T(1)). Adolescents' self-reports of parenting and substance use were assessed at T(0). Between assessment points, we experimentally varied the reliability of delayed reward promises, measuring the impact of this intervention on DD and neural value processing at T(1). In the correlational part, same-sex parent reward inconsistency was associated with steeper DD and an attenuated subjective value (SV) representation in the nucleus accumbens (NAcc) and ventromedial prefrontal cortex (vmPFC). Steeper DD was in turn associated with alcohol use during the past year. In the experimental part, the reward inconsistency manipulation resulted in an attenuation of the NAcc SV representation, similar to the parental inconsistency effect. Together, our correlational and experimental findings raise new light on how parents may influence their children's degree of impulsivity, making parenting a potential target in addiction prevention.
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spelling pubmed-40122842014-05-07 Parental inconsistency, impulsive choice and neural value representations in healthy adolescents Schneider, S Peters, J Peth, J M Büchel, C Transl Psychiatry Original Article A well-characterized potential marker for addiction is impulsive choice, stably measured by delay discounting (DD) paradigms. While genetic influences partly account for inter-individual variance in impulsivity, environmental factors such as parenting practices may have an important role. The present study investigates how inconsistent fulfillment of delayed reward promises impacts on DD. A combined correlational and experimental functional magnetic resonance imaging (fMRI) design was performed in a sample of 48 healthy adolescents (13–15 years). More specifically, neural activation during a DD task was investigated at two assessment points (T(0) and T(1)). Adolescents' self-reports of parenting and substance use were assessed at T(0). Between assessment points, we experimentally varied the reliability of delayed reward promises, measuring the impact of this intervention on DD and neural value processing at T(1). In the correlational part, same-sex parent reward inconsistency was associated with steeper DD and an attenuated subjective value (SV) representation in the nucleus accumbens (NAcc) and ventromedial prefrontal cortex (vmPFC). Steeper DD was in turn associated with alcohol use during the past year. In the experimental part, the reward inconsistency manipulation resulted in an attenuation of the NAcc SV representation, similar to the parental inconsistency effect. Together, our correlational and experimental findings raise new light on how parents may influence their children's degree of impulsivity, making parenting a potential target in addiction prevention. Nature Publishing Group 2014-04 2014-04-15 /pmc/articles/PMC4012284/ /pubmed/24736798 http://dx.doi.org/10.1038/tp.2014.20 Text en Copyright © 2014 Macmillan Publishers Limited http://creativecommons.org/licenses/by-nc-nd/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/
spellingShingle Original Article
Schneider, S
Peters, J
Peth, J M
Büchel, C
Parental inconsistency, impulsive choice and neural value representations in healthy adolescents
title Parental inconsistency, impulsive choice and neural value representations in healthy adolescents
title_full Parental inconsistency, impulsive choice and neural value representations in healthy adolescents
title_fullStr Parental inconsistency, impulsive choice and neural value representations in healthy adolescents
title_full_unstemmed Parental inconsistency, impulsive choice and neural value representations in healthy adolescents
title_short Parental inconsistency, impulsive choice and neural value representations in healthy adolescents
title_sort parental inconsistency, impulsive choice and neural value representations in healthy adolescents
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012284/
https://www.ncbi.nlm.nih.gov/pubmed/24736798
http://dx.doi.org/10.1038/tp.2014.20
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