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Sustained AAV-mediated overexpression of CRF in the central amygdala diminishes the depressive-like state associated with nicotine withdrawal

Smoking cessation leads to a dysphoric state and this increases the risk for relapse. Animal studies indicate that the dysphoric state associated with nicotine withdrawal is at least partly mediated by an increase in corticotropin-releasing factor (CRF) release in the central nucleus of the amygdala...

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Detalles Bibliográficos
Autores principales:	Qi, X, Shan, Z, Ji, Y, Guerra, V, Alexander, J C, Ormerod, B K, Bruijnzeel, A W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012288/ https://www.ncbi.nlm.nih.gov/pubmed/24755994 http://dx.doi.org/10.1038/tp.2014.25

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