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Synthesis and Anti-Tuberculosis Activity of the Marine Natural Product Caulerpin and Its Analogues

Caulerpin (1a), a bis-indole alkaloid from the marine algal Caulerpa sp., was synthesized in three reaction steps with an overall yield of 11%. The caulerpin analogues (1b–1g) were prepared using the same synthetic pathway with overall yields between 3% and 8%. The key reaction involved a radical ox...

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Detalles Bibliográficos
Autores principales: Canché Chay, Cristina I., Gómez Cansino, Rocío, Espitia Pinzón, Clara I., Torres-Ochoa, Rubén O., Martínez, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012461/
https://www.ncbi.nlm.nih.gov/pubmed/24681629
http://dx.doi.org/10.3390/md12041757

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