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EGFR endocytosis is a novel therapeutic target in lung cancer with wild-type EGFR

Oncogenic alterations of epidermal growth factor receptor (EGFR) signaling are frequently observed in lung cancer patients with worse differentiation and poor prognosis. However, the therapeutic efficacy of EGFR-tyrosine kinase inhibitors (TKIs) is currently limited in selected patients with EGFR mu...

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Detalles Bibliográficos
Autores principales: Jo, Ukhyun, Park, Kyong Hwa, Whang, Young Mi, Sung, Jae Sook, Won, Nam Hee, Park, Jong Kuk, Kim, Yeul Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012721/
https://www.ncbi.nlm.nih.gov/pubmed/24658031