Chronic Wasting Disease Agents in Nonhuman Primates

Chronic wasting disease is a prion disease of cervids. Assessment of its zoonotic potential is critical. To evaluate primate susceptibility, we tested monkeys from 2 genera. We found that 100% of intracerebrally inoculated and 92% of orally inoculated squirrel monkeys were susceptible, but cynomolgu...

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Autores principales: Race, Brent, Meade-White, Kimberly D., Phillips, Katie, Striebel, James, Race, Richard, Chesebro, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2014
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012792/
https://www.ncbi.nlm.nih.gov/pubmed/24751215
http://dx.doi.org/10.3201/eid2005.130778
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author Race, Brent
Meade-White, Kimberly D.
Phillips, Katie
Striebel, James
Race, Richard
Chesebro, Bruce
author_facet Race, Brent
Meade-White, Kimberly D.
Phillips, Katie
Striebel, James
Race, Richard
Chesebro, Bruce
author_sort Race, Brent
collection PubMed
description Chronic wasting disease is a prion disease of cervids. Assessment of its zoonotic potential is critical. To evaluate primate susceptibility, we tested monkeys from 2 genera. We found that 100% of intracerebrally inoculated and 92% of orally inoculated squirrel monkeys were susceptible, but cynomolgus macaques were not, suggesting possible low risk for humans.
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spelling pubmed-40127922014-05-09 Chronic Wasting Disease Agents in Nonhuman Primates Race, Brent Meade-White, Kimberly D. Phillips, Katie Striebel, James Race, Richard Chesebro, Bruce Emerg Infect Dis Dispatch Chronic wasting disease is a prion disease of cervids. Assessment of its zoonotic potential is critical. To evaluate primate susceptibility, we tested monkeys from 2 genera. We found that 100% of intracerebrally inoculated and 92% of orally inoculated squirrel monkeys were susceptible, but cynomolgus macaques were not, suggesting possible low risk for humans. Centers for Disease Control and Prevention 2014-05 /pmc/articles/PMC4012792/ /pubmed/24751215 http://dx.doi.org/10.3201/eid2005.130778 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Race, Brent
Meade-White, Kimberly D.
Phillips, Katie
Striebel, James
Race, Richard
Chesebro, Bruce
Chronic Wasting Disease Agents in Nonhuman Primates
title Chronic Wasting Disease Agents in Nonhuman Primates
title_full Chronic Wasting Disease Agents in Nonhuman Primates
title_fullStr Chronic Wasting Disease Agents in Nonhuman Primates
title_full_unstemmed Chronic Wasting Disease Agents in Nonhuman Primates
title_short Chronic Wasting Disease Agents in Nonhuman Primates
title_sort chronic wasting disease agents in nonhuman primates
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012792/
https://www.ncbi.nlm.nih.gov/pubmed/24751215
http://dx.doi.org/10.3201/eid2005.130778
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