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Efficacy and Dose-Dependent Safety of Intra-Arterial Delivery of Mesenchymal Stem Cells in a Rodent Stroke Model
Intra-arterial (IA) delivery of mesenchymal stem cells (MSCs) for acute ischemic stroke is attractive for clinical translation. However, studies using rat model of stroke have demonstrated that IA MSCs delivery can decrease middle cerebral artery (MCA) flow, which may limit its clinical translation....
Autores principales: | Yavagal, Dileep R., Lin, Baowan, Raval, Ami P., Garza, Philip S., Dong, Chuanhui, Zhao, Weizhao, Rangel, Erika B., McNiece, Ian, Rundek, Tatjana, Sacco, Ralph L., Perez-Pinzon, Miguel, Hare, Joshua M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012944/ https://www.ncbi.nlm.nih.gov/pubmed/24807059 http://dx.doi.org/10.1371/journal.pone.0093735 |
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