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Development of a Transgenic Plasmodium berghei Line (Pb(pfpkg)) Expressing the P. falciparum cGMP-Dependent Protein Kinase, a Novel Antimalarial Drug Target
With the inevitable selection of resistance to antimalarial drugs in treated populations, there is a need for new medicines to enter the clinic and new targets to progress through the drug discovery pipeline. In this study we set out to develop a transgenic rodent model for testing inhibitors of the...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013051/ https://www.ncbi.nlm.nih.gov/pubmed/24805991 http://dx.doi.org/10.1371/journal.pone.0096923 |