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Identification of Isoxsuprine Hydrochloride as a Neuroprotectant in Ischemic Stroke through Cell-Based High-Throughput Screening
Stroke is a leading cause of death and disability and treatment options are limited. A promising approach to accelerate the development of new therapeutics is the use of high-throughput screening of chemical libraries. Using a cell-based high-throughput oxygen-glucose deprivation (OGD) model, we eva...
Autores principales: | Hill, Jeff W., Thompson, Jeffrey F., Carter, Mark B., Edwards, Bruce S., Sklar, Larry A., Rosenberg, Gary A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013073/ https://www.ncbi.nlm.nih.gov/pubmed/24804769 http://dx.doi.org/10.1371/journal.pone.0096761 |
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