Cargando…

Piperine Causes G1 Phase Cell Cycle Arrest and Apoptosis in Melanoma Cells through Checkpoint Kinase-1 Activation

In this study, we determined the cytotoxic effects of piperine, a major constituent of black and long pepper in melanoma cells. Piperine treatment inhibited the growth of SK MEL 28 and B16 F0 cells in a dose and time-dependent manner. The growth inhibitory effects of piperine were mediated by cell c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fofaria, Neel M., Kim, Sung-Hoon, Srivastava, Sanjay K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013113/ https://www.ncbi.nlm.nih.gov/pubmed/24804719 http://dx.doi.org/10.1371/journal.pone.0094298

Ejemplares similares

Critical role of STAT3 in melanoma metastasis through anoikis resistance
por: Fofaria, Neel M., et al.
Publicado: (2014)

Overexpression of Mcl-1 confers resistance to BRAF(V600E) inhibitors alone and in combination with MEK1/2 inhibitors in melanoma
por: Fofaria, Neel M., et al.
Publicado: (2015)

Eimeria tenella ROP kinase EtROP1 induces G0/G1 cell cycle arrest and inhibits host cell apoptosis
por: Diallo, Mamadou Amadou, et al.
Publicado: (2019)

Casticin induces apoptosis and G0/G1 cell cycle arrest in gallbladder cancer cells
por: Song, Xiao-ling, et al.
Publicado: (2017)

Cinobufagin Induces Cell Cycle Arrest at the G2/M Phase and Promotes Apoptosis in Malignant Melanoma Cells
por: Pan, Zhaohai, et al.
Publicado: (2019)

Moxidectin inhibits glioma cell viability by inducing G0/G1 cell cycle arrest and apoptosis
por: Song, Dandan, et al.
Publicado: (2018)

Inhibition of β-Catenin signaling suppresses pancreatic tumor growth by disrupting nuclear β-Catenin/TCF-1 complex: Critical role of STAT-3
por: Pramanik, Kartick C., et al.
Publicado: (2015)

Cyclin-dependent kinase 1 disruption inhibits angiogenesis by inducing cell cycle arrest and apoptosis
por: Gao, Xin, et al.
Publicado: (2019)

Fusarochromanone Induces G(1) Cell Cycle Arrest and Apoptosis in COS7 and HEK293 Cells
por: Gu, Ying, et al.
Publicado: (2014)

Genes involved in cell cycle G1 checkpoint control are frequently mutated in human melanoma metastases.
por: Platz, A., et al.
Publicado: (1996)

Chalcone-Acridine Hybrid Suppresses Melanoma Cell Progression via G2/M Cell Cycle Arrest, DNA Damage, Apoptosis, and Modulation of MAP Kinases Activity
por: Gazdova, Maria, et al.
Publicado: (2022)

Naphthoquinones from Onosma paniculata Induce Cell-Cycle Arrest and Apoptosis in Melanoma Cells
por: Kretschmer, Nadine, et al.
Publicado: (2012)

Cell Cycle Arrest by a Natural Product via G2/M Checkpoint
por: Luk, Sharon Chui-Wah, et al.
Publicado: (2005)

Propranolol induced G0/G1/S phase arrest and apoptosis in melanoma cells via AKT/MAPK pathway
por: Zhou, Chengfang, et al.
Publicado: (2016)

Activation of ATM/Chk1 by curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer cells
por: Sahu, R P, et al.
Publicado: (2009)

Piperine–Chlorogenic Acid Hybrid Inhibits the Proliferation of the SK-MEL-147 Melanoma Cells by Modulating Mitotic Kinases
por: Pressete, Carolina Girotto, et al.
Publicado: (2023)

Ponicidin suppresses HT29 cell growth via the induction of G1 cell cycle arrest and apoptosis
por: DU, JIE, et al.
Publicado: (2015)

Protosappanin B promotes apoptosis and causes G(1) cell cycle arrest in human bladder cancer cells
por: Yang, Xihua, et al.
Publicado: (2019)

Targeting the overexpressed ROC1 induces G2 cell cycle arrest and apoptosis in esophageal cancer cells
por: Zhang, Jingyang, et al.
Publicado: (2017)

Geranium thunbergii extract-induced G1 phase cell cycle arrest and apoptosis in gastric cancer cells
por: Lee, Hana, et al.
Publicado: (2019)

Combination of anlotinib and gemcitabine promotes the G0/G1 cell cycle arrest and apoptosis of intrahepatic cholangiocarcinoma in vitro
por: Fan, Shanshan, et al.
Publicado: (2021)

Ailanthone Induces Cell Cycle Arrest and Apoptosis in Melanoma B16 and A375 Cells
por: Liu, Wenjing, et al.
Publicado: (2019)

Modelling the onset of senescence at the G1/S cell cycle checkpoint
por: Mombach, José CM, et al.
Publicado: (2014)

TERT promoter regulating melittin expression induces apoptosis and G(0)/G(1) cell cycle arrest in esophageal carcinoma cells
por: Zhou, Chao, et al.
Publicado: (2021)

Targeting mixed lineage kinases in ER-positive breast cancer cells leads to G2/M cell cycle arrest and apoptosis
por: Wang, Limin, et al.
Publicado: (2013)

Downregulation of PLK4 expression induces apoptosis and G0/G1‐phase cell cycle arrest in keloid fibroblasts
por: Huang, Ru‐Lin, et al.
Publicado: (2022)

Kaempferol Induces G2/M Cell Cycle Arrest via Checkpoint Kinase 2 and Promotes Apoptosis via Death Receptors in Human Ovarian Carcinoma A2780/CP70 Cells
por: Gao, Ying, et al.
Publicado: (2018)

Impact of Mitochondria-Mediated Apoptosis in U251 Cell Cycle Arrest in G1 Stage and Caspase Activation
por: Zhang, Lei, et al.
Publicado: (2015)

Luteolin Shifts Oxaliplatin-Induced Cell Cycle Arrest at G(0)/G(1) to Apoptosis in HCT116 Human Colorectal Carcinoma Cells
por: Jang, Chan Ho, et al.
Publicado: (2019)

Cold atmospheric plasma selectively induces G(0)/G(1) cell cycle arrest and apoptosis in AR-independent prostate cancer cells
por: Hua, Dong, et al.
Publicado: (2021)

Panduratin A Inhibits Cell Proliferation by Inducing G0/G1 Phase Cell Cycle Arrest and Induces Apoptosis in Breast Cancer Cells
por: Liu, Qiuming, et al.
Publicado: (2018)

Tectorigenin Inhibits Glioblastoma Proliferation by G0/G1 Cell Cycle Arrest
por: Yeh, Liang-Tsai, et al.
Publicado: (2020)

The Inhibition of Polo Kinase by Matrimony Maintains G2 Arrest in the Meiotic Cell Cycle
por: Xiang, Youbin, et al.
Publicado: (2007)

Down-regulation of STAT3 induces the apoptosis and G1 cell cycle arrest in esophageal carcinoma ECA109 cells
por: Zhou, Chao, et al.
Publicado: (2018)

CMPD1 inhibited human gastric cancer cell proliferation by inducing apoptosis and G2/M cell cycle arrest
por: Li, Yu, et al.
Publicado: (2018)

Ganetespib induces G2/M cell cycle arrest and apoptosis in gastric cancer cells through targeting of receptor tyrosine kinase signaling
por: Lee, Harry, et al.
Publicado: (2017)

Light‐Controlled Cell‐Cycle Arrest and Apoptosis
por: Uhl, Edgar, et al.
Publicado: (2020)

Mechanisms of Cell Cycle Arrest and Apoptosis in Glioblastoma
por: Gousias, Konstantinos, et al.
Publicado: (2022)

Carbon ions of different linear energy transfer (LET) values induce apoptosis & G2 cell cycle arrest in radio-resistant melanoma cells
por: Jelena, Žakula, et al.
Publicado: (2016)

DCZ0814 induces apoptosis and G0/G1 phase cell cycle arrest in myeloma by dual inhibition of mTORC1/2
por: Kong, Yuanyuan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_h5ol4menqfgnj2fan17e7ubaj8