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Cell Invasion in the Spheroid Sprouting Assay: A Spatial Organisation Analysis Adaptable to Cell Behaviour

The endothelial cell spheroid assay provides a suitable in vitro model to study (lymph) angiogenesis and test pro- and anti-(lymph) angiogenic factors or drugs. Usually, the extent of cell invasion, observed through optical microscopy, is measured. The present study proposes the spatial distribution...

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Detalles Bibliográficos
Autores principales: Blacher, Silvia, Erpicum, Charlotte, Lenoir, Bénédicte, Paupert, Jenny, Moraes, Gustavo, Ormenese, Sandra, Bullinger, Eric, Noel, Agnès
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013117/
https://www.ncbi.nlm.nih.gov/pubmed/24806521
http://dx.doi.org/10.1371/journal.pone.0097019