Calorie Restriction Decreases Murine and Human Pancreatic Tumor Cell Growth, Nuclear Factor-κB Activation, and Inflammation-Related Gene Expression in an Insulin-like Growth Factor-1−Dependent Manner

Calorie restriction (CR) prevents obesity and has potent anticancer effects that may be mediated through its ability to reduce serum growth and inflammatory factors, particularly insulin-like growth factor (IGF)-1 and protumorigenic cytokines. IGF-1 is a nutrient-responsive growth factor that activa...

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Detalles Bibliográficos
Autores principales: Harvey, Alison E., Lashinger, Laura M., Hays, Drew, Harrison, Lauren M., Lewis, Kimberly, Fischer, Susan M., Hursting, Stephen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013119/
https://www.ncbi.nlm.nih.gov/pubmed/24804677
http://dx.doi.org/10.1371/journal.pone.0094151

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