Cargando…
MLL1/WDR5 complex in leukemogenesis and epigenetic regulation
MLL1 is a histone H3Lys4 methyltransferase and forms a complex with WDR5 and other components. It plays important roles in developmental events, transcriptional regulation, and leukemogenesis. MLL1 -fusion proteins resulting from chromosomal translocations are molecular hallmarks of a special type o...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Sun Yat-sen University Cancer Center
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013350/ https://www.ncbi.nlm.nih.gov/pubmed/21439245 http://dx.doi.org/10.5732/cjc.011.10055 |