Radiotherapy of unicentric mediastinal Castleman's disease

Castleman's disease is a slowly progressive and rare lymphoproliferative disorder. Here, we report a 55-year-old woman with superior mediastinal Castleman's disease being misdiagnosed for a long term. We found a 4.3 cm mass localized in the superior mediastinum accompanied with severe clin...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yue-Min, Liu, Peng-Hui, Zhang, Yu-Hai, Xia, Huo-Sheng, Li, Liang-Liang, Qu, Yi-Mei, Wu, Yong, Han, Shou-Yun, Liao, Guo-Qing, Pu, Yong-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sun Yat-sen University Cancer Center 2011
Materias:
Case Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013400/
https://www.ncbi.nlm.nih.gov/pubmed/21527068
http://dx.doi.org/10.5732/cjc.010.10402
Descripción
Sumario:Castleman's disease is a slowly progressive and rare lymphoproliferative disorder. Here, we report a 55-year-old woman with superior mediastinal Castleman's disease being misdiagnosed for a long term. We found a 4.3 cm mass localized in the superior mediastinum accompanied with severe clinical symptoms. The patient underwent an exploratory laparotomy, but the mass failed to be totally excised. Pathologic examination revealed a mediastinal mass of Castleman's disease. After radiotherapy of 30 Gy by 15 fractions, the patient no longer presented previous symptoms. At 3 months after radiotherapy of 60 Gy by 30 fractions, Computed tomography of the chest showed significantly smaller mass, indicating partial remission. Upon a 10-month follow-up, the patient was alive and free of symptoms.

Ejemplares similares