Tumor shrinkage by cyclopamine tartrate through inhibiting hedgehog signaling

The link of hedgehog (Hh) signaling activation to human cancer and synthesis of a variety of Hh signaling inhibitors raise great expectation that inhibiting Hh signaling may be effective in human cancer treatment. Cyclopamine (Cyc), an alkaloid from the Veratrum plant, is a specific natural product...

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Detalles Bibliográficos
Autores principales: Fan, Qipeng, Gu, Dongsheng, He, Miao, Liu, Hailan, Sheng, Tao, Xie, Guorui, Li, Ching-xin, Zhang, Xiaoli, Wainwright, Brandon, Garrossian, Arash, Garrossian, Massoud, Gardner, Dale, Xie, Jingwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sun Yat-sen University Cancer Center 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013422/
https://www.ncbi.nlm.nih.gov/pubmed/21718593
http://dx.doi.org/10.5732/cjc.011.10157

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