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Small GTPase CDC-42 promotes apoptotic cell corpse clearance in response to PAT-2 and CED-1 in C. elegans

The rapid clearance of dying cells is important for the well-being of multicellular organisms. In C. elegans, cell corpse removal is mainly mediated by three parallel engulfment signaling cascades. These pathways include two small GTPases, MIG-2/RhoG and CED-10/Rac1. Here we present the identificati...

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Detalles Bibliográficos
Autores principales: Neukomm, L J, Zeng, S, Frei, A P, Huegli, P A, Hengartner, M O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013519/
https://www.ncbi.nlm.nih.gov/pubmed/24632947
http://dx.doi.org/10.1038/cdd.2014.23