Evaluation of a Method for Nitrotyrosine Site Identification and Relative Quantitation Using a Stable Isotope-Labeled Nitrated Spike-In Standard and High Resolution Fourier Transform MS and MS/MS Analysis

The overproduction of reactive oxygen and nitrogen species (ROS and RNS) can have deleterious effects in the cell, including structural and possible activity-altering modifications to proteins. Peroxynitrite is one such RNS that can result in a specific protein modification, nitration of tyrosine re...

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Detalles Bibliográficos
Autores principales: Seeley, Kent W., Fertig, Alison R., Dufresne, Craig P., Pinho, Joao P. C., Stevens, Stanley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013627/
https://www.ncbi.nlm.nih.gov/pubmed/24736779
http://dx.doi.org/10.3390/ijms15046265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013627/
https://www.ncbi.nlm.nih.gov/pubmed/24736779
http://dx.doi.org/10.3390/ijms15046265

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