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FoxP3(+) regulatory T cells promote influenza-specific Tfh responses by controlling IL-2 availability

Here we test the role of FoxP3(+) regulatory T cells (Tregs) in controlling T follicular helper (Tfh) and germinal-center (GC) B cell responses to influenza. In contrast to the idea that Tregs suppress T cell responses, we find that Treg depletion severely reduces the Tfh cell response to influenza...

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Detalles Bibliográficos
Autores principales:	León, Beatriz, Bradley, John E., Lund, Frances E., Randall, Troy D., Ballesteros-Tato, André
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013682/ https://www.ncbi.nlm.nih.gov/pubmed/24633065 http://dx.doi.org/10.1038/ncomms4495

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