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T(2)-weighted MRI detects presymptomatic pathology in the SOD1 mouse model of ALS

Neuroinflammation has been identified as a potential therapeutic target in amyotrophic lateral sclerosis (ALS), but relevant biomarkers are needed. The superoxide dismutase (SOD1)(G93A) transgenic mouse model of ALS offers a unique opportunity to study and potentially manipulate presymptomatic patho...

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Detalles Bibliográficos
Autores principales:	Evans, Matthew C, Serres, Sébastien, Khrapitchev, Alexandre A, Stolp, Helen B, Anthony, Daniel C, Talbot, Kevin, Turner, Martin R, Sibson, Nicola R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013759/ https://www.ncbi.nlm.nih.gov/pubmed/24496176 http://dx.doi.org/10.1038/jcbfm.2014.19

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