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Dioscin promotes osteoblastic proliferation and differentiation via Lrp5 and ER pathway in mouse and human osteoblast-like cell lines

BACKGROUND: Dioscin, a typical steroid saponin, is isolated from Dioscorea nipponica Makino and Dioscorea zingiberensis Wright. It has estrogenic activity and many studies have also reported that dioscorea plants have an effect in preventing and treating osteoporosis. However, the molecular mechanis...

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Detalles Bibliográficos
Autores principales:	Zhang, Chunfang, Peng, Jinyong, Wu, Shan, Jin, Yue, Xia, Fan, Wang, Changyuan, Liu, Kexin, Sun, Huijun, Liu, Mozhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014146/ https://www.ncbi.nlm.nih.gov/pubmed/24742230 http://dx.doi.org/10.1186/1423-0127-21-30

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