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Comprehensive Characterization of (S)GTP-Binding Proteins by Orthogonal Quantitative (S)GTP-Affinity Profiling and (S)GTP/GTP Competition Assays
[Image: see text] Thiopurine drugs are widely used as antileukemic drugs and immunosuppressive agents, and 6-thioguanosine triphosphate ((S)GTP) is a major metabolite for these drugs. Recent studies have suggested that thiopurine drugs may exert their cytotoxic effects partly through binding of (S)G...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014148/ https://www.ncbi.nlm.nih.gov/pubmed/24689502 http://dx.doi.org/10.1021/ac500588q |