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Transgenic expression of Map3k4 rescues T-associated sex reversal (Tas) in mice

Disorders of sex development in the human population range in severity from mild genital defects to gonadal sex reversal. XY female development has been associated with heterozygous mutations in several genes, including SOX9, WT1 and MAP3K1. In contrast, XY sex reversal in mice usually requires comp...

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Detalles Bibliográficos
Autores principales:	Warr, Nick, Siggers, Pam, Carré, Gwenn-Aël, Bogani, Debora, Brixey, Rachel, Akiyoshi, Mika, Tachibana, Makoto, Teboul, Lydia, Wells, Sara, Sanderson, Jeremy, Greenfield, Andy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014197/ https://www.ncbi.nlm.nih.gov/pubmed/24452333 http://dx.doi.org/10.1093/hmg/ddu020

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