Involvement of c-KIT mutation in the development of gastrointestinal stromal tumors through proliferation promotion and apoptosis inhibition

The aim of this study was to discuss the role of c-KIT mutation in the pathogenesis of gastrointestinal stromal tumors (GISTs) and analyze its correlation with proliferation and apoptosis. c-KIT and PDGFRA genotypes were examined by deoxyribonucleic acid sequencing. Immunohistochemistry was performe...

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Detalles Bibliográficos
Autores principales: Ma, Ying-Yu, Yu, Sheng, He, Xu-Jun, Xu, Yuan, Wu, Fang, Xia, Ying-Jie, Guo, Kun, Wang, Hui-Ju, Ye, Zai-Yuan, Zhang, Wei, Tao, Hou-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014364/
https://www.ncbi.nlm.nih.gov/pubmed/24833907
http://dx.doi.org/10.2147/OTT.S60458

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