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Pain severity is associated with muscle strength and peak oxygen uptake in adults with fibromyalgia
BACKGROUND: The associations between pain, lower extremity strength, and aerobic conditioning have not been widely investigated in adults with fibromyalgia (FM). The principle objective of this study was to investigate the relationship between pain severity and knee strength in patients seeking trea...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014369/ https://www.ncbi.nlm.nih.gov/pubmed/24833914 http://dx.doi.org/10.2147/JPR.S61312 |
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author | Hooten, W Michael Smith, Jolene M Eldrige, Jason S Olsen, David A Mauck, W David Moeschler, Susan M |
author_facet | Hooten, W Michael Smith, Jolene M Eldrige, Jason S Olsen, David A Mauck, W David Moeschler, Susan M |
author_sort | Hooten, W Michael |
collection | PubMed |
description | BACKGROUND: The associations between pain, lower extremity strength, and aerobic conditioning have not been widely investigated in adults with fibromyalgia (FM). The principle objective of this study was to investigate the relationship between pain severity and knee strength in patients seeking treatment for FM. A secondary objective was to investigate the relationship between pain scores and aerobic conditioning. METHODS: Three measures of knee strength (isokinetic extensor, isokinetic flexor, isometric extensor) were quantified in the dominant leg of 69 adults with FM using a dynamometer at speeds of 60 degrees per second (60°/s) and 180°/s. Peak oxygen uptake (VO(2)) was assessed using a cycle ergometer, and pain was assessed using the pain severity subscale of the Multidimensional Pain Inventory. RESULTS: In univariable linear regression analyses using pain severity as the dependent variable, lesser values of isokinetic knee extensor strength at 60°/s (P=0.041) and 180°/s (P=0.010), isokinetic knee flexor strength at 60°/s (P=0.028) and 180°/s (P=0.003), and peak VO(2) uptake (P=0.031) were predictive of greater pain severity scores. In multiple variable linear regression models adjusted for age, sex, body mass index, and opioid use, the following associations retained statistical significance; isokinetic knee extensor strength at 60°/s (P=0.020) and 180°/s (P=0.003), isokinetic knee flexor strength at 60°/s (P=0.015) and 180°/s (P=0.001), and peak VO(2) uptake (P=0.014). However, no significant associations were found between pain severity and isometric knee extensor strength. CONCLUSION: The main findings from this study were that lesser values of isokinetic knee strength and peak VO(2) uptake were predictive of greater pain severity scores. These results build on the findings of previous investigations, but ongoing research is needed to further characterize the effects of strength and peak VO(2) uptake on the pathophysiology of FM. |
format | Online Article Text |
id | pubmed-4014369 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-40143692014-05-15 Pain severity is associated with muscle strength and peak oxygen uptake in adults with fibromyalgia Hooten, W Michael Smith, Jolene M Eldrige, Jason S Olsen, David A Mauck, W David Moeschler, Susan M J Pain Res Original Research BACKGROUND: The associations between pain, lower extremity strength, and aerobic conditioning have not been widely investigated in adults with fibromyalgia (FM). The principle objective of this study was to investigate the relationship between pain severity and knee strength in patients seeking treatment for FM. A secondary objective was to investigate the relationship between pain scores and aerobic conditioning. METHODS: Three measures of knee strength (isokinetic extensor, isokinetic flexor, isometric extensor) were quantified in the dominant leg of 69 adults with FM using a dynamometer at speeds of 60 degrees per second (60°/s) and 180°/s. Peak oxygen uptake (VO(2)) was assessed using a cycle ergometer, and pain was assessed using the pain severity subscale of the Multidimensional Pain Inventory. RESULTS: In univariable linear regression analyses using pain severity as the dependent variable, lesser values of isokinetic knee extensor strength at 60°/s (P=0.041) and 180°/s (P=0.010), isokinetic knee flexor strength at 60°/s (P=0.028) and 180°/s (P=0.003), and peak VO(2) uptake (P=0.031) were predictive of greater pain severity scores. In multiple variable linear regression models adjusted for age, sex, body mass index, and opioid use, the following associations retained statistical significance; isokinetic knee extensor strength at 60°/s (P=0.020) and 180°/s (P=0.003), isokinetic knee flexor strength at 60°/s (P=0.015) and 180°/s (P=0.001), and peak VO(2) uptake (P=0.014). However, no significant associations were found between pain severity and isometric knee extensor strength. CONCLUSION: The main findings from this study were that lesser values of isokinetic knee strength and peak VO(2) uptake were predictive of greater pain severity scores. These results build on the findings of previous investigations, but ongoing research is needed to further characterize the effects of strength and peak VO(2) uptake on the pathophysiology of FM. Dove Medical Press 2014-05-03 /pmc/articles/PMC4014369/ /pubmed/24833914 http://dx.doi.org/10.2147/JPR.S61312 Text en © 2014 Hooten et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Original Research Hooten, W Michael Smith, Jolene M Eldrige, Jason S Olsen, David A Mauck, W David Moeschler, Susan M Pain severity is associated with muscle strength and peak oxygen uptake in adults with fibromyalgia |
title | Pain severity is associated with muscle strength and peak oxygen uptake in adults with fibromyalgia |
title_full | Pain severity is associated with muscle strength and peak oxygen uptake in adults with fibromyalgia |
title_fullStr | Pain severity is associated with muscle strength and peak oxygen uptake in adults with fibromyalgia |
title_full_unstemmed | Pain severity is associated with muscle strength and peak oxygen uptake in adults with fibromyalgia |
title_short | Pain severity is associated with muscle strength and peak oxygen uptake in adults with fibromyalgia |
title_sort | pain severity is associated with muscle strength and peak oxygen uptake in adults with fibromyalgia |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014369/ https://www.ncbi.nlm.nih.gov/pubmed/24833914 http://dx.doi.org/10.2147/JPR.S61312 |
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