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Fine Tuning of the UPR by the Ubiquitin Ligases Siah1/2

The endoplasmic reticulum (ER) responds to changes in intracellular homeostasis through activation of the unfolded protein response (UPR). Yet, it is not known how UPR-signaling coordinates adaptation versus cell death. Previous studies suggested that signaling through PERK/ATF4 is required for cell...

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Detalles Bibliográficos
Autores principales:	Scortegagna, Marzia, Kim, Hyungsoo, Li, Jian-Liang, Yao, Hang, Brill, Laurence M., Han, Jaeseok, Lau, Eric, Bowtell, David, Haddad, Gabriel, Kaufman, Randal J., Ronai, Ze'ev A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014425/ https://www.ncbi.nlm.nih.gov/pubmed/24809345 http://dx.doi.org/10.1371/journal.pgen.1004348

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