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Epigenetic Changes Modulate Schistosome Egg Formation and Are a Novel Target for Reducing Transmission of Schistosomiasis
Treatment and control of schistosomiasis relies on the only available drug, praziquantel, and the search for alternative chemotherapeutic agents is therefore urgent. Egg production is required for the transmission and immunopathology of schistosomiasis and females of S. mansoni lay 300 eggs daily. A...
Autores principales: | Carneiro, Vitor Coutinho, de Abreu da Silva, Isabel Caetano, Torres, Eduardo José Lopes, Caby, Stephany, Lancelot, Julien, Vanderstraete, Mathieu, Furdas, Silviya D., Jung, Manfred, Pierce, Raymond J., Fantappié, Marcelo Rosado |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014452/ https://www.ncbi.nlm.nih.gov/pubmed/24809504 http://dx.doi.org/10.1371/journal.ppat.1004116 |
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