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Epstein-Barr Virus Down-Regulates Tumor Suppressor DOK1 Expression
The DOK1 tumor suppressor gene encodes an adapter protein that acts as a negative regulator of several signaling pathways. We have previously reported that DOK1 expression is up-regulated upon cellular stress, via the transcription factor E2F1, and down-regulated in a variety of human malignancies d...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014463/ https://www.ncbi.nlm.nih.gov/pubmed/24809689 http://dx.doi.org/10.1371/journal.ppat.1004125 |