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The Sonic Hedgehog Signaling Pathway Induces Myopic Development by Activating Matrix Metalloproteinase (MMP)-2 in Guinea Pigs

PURPOSE: To investigate whether the Sonic hedgehog (Shh) signaling induces myopic development by increasing the expression of matrix metalloproteinase (MMP)-2 in guinea pigs. METHODS: A translucent diffuser was glued onto the right eye to induce form-deprivation myopia (FDM) in 10 guinea pigs. Four...

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Detalles Bibliográficos
Autores principales:	Chen, Minjie, Qian, Yishan, Dai, Jinhui, Chu, Renyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014572/ https://www.ncbi.nlm.nih.gov/pubmed/24810957 http://dx.doi.org/10.1371/journal.pone.0096952

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