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Analysis of Determinants in Filovirus Glycoproteins Required for Tetherin Antagonism

The host cell protein tetherin can restrict the release of enveloped viruses from infected cells. The HIV-1 protein Vpu counteracts tetherin by removing it from the site of viral budding, the plasma membrane, and this process depends on specific interactions between the transmembrane domains of Vpu...

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Detalles Bibliográficos
Autores principales: Gnirß, Kerstin, Fiedler, Marie, Krämer-Kühl, Annika, Bolduan, Sebastian, Mittler, Eva, Becker, Stephan, Schindler, Michael, Pöhlmann, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014715/
https://www.ncbi.nlm.nih.gov/pubmed/24721789
http://dx.doi.org/10.3390/v6041654